Contraindications

Not to be used in

· Breastfeeding
· Children and adolescents under 18 years of age
· Closed angle glaucoma
· History of blocked arteries in the extremities
· History of coronary artery disease
· History of drug, alcohol or medication dependence or abuse
· History of heart failure
· History of increased heart rate (tachycardia)
· History of irregular heart beats (arrhythmias)
· History of small temporary strokes
· History of stroke
· Hyperthyroidism
· Obesity caused by a medical condition
· People over 65 years of age
· People who have taken antidepressant, antipsychotic or appetite suppressant medicines, or tryptophan to aid sleep, in the last 14 days
· People receiving monoamine oxidase (MAO) inhibitors.
· People with a history of anorexia nervosa
· People with a history of bulimia nervosa
· Pregnancy
· Psychiatric disorders
· Severely decreased kidney function
· Severely decreased liver function
· Syndrome characterised by involuntary repetition of speech, particularly obscene or vulgar words (Gilles de la Tourette's syndrome)
· Tumour of the adrenal gland (phaeochromocytoma)
· Uncontrolled high blood pressure
· Urinary retention caused by an enlarged prostate gland

Reductil should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using Sibutramine and inform your doctor or pharmacist immediately.

Known hypersensitivity to sibutramine or to any other ingredient of the preparation.

Pregnancy and Breastfeeding

· The safety of Reductil in pregnancy has not been established. It should not be taken by women who are pregnant, and women who could get pregnant should use an effective method of contraception to prevent pregnancy while taking this medicine. Seek further medical advice from your doctor.
· There is no information available about the safety of Reductil during breastfeeding. For this reason, the manufacturer states that it should not be used during breastfeeding. Seek medical advice from your doctor.